Personal + Lab Gill Bejerano, Assistant Professor of Developmental Biology and of Computer Science. Dr. Bejerano’s laboratory focuses on the study of the human genome. He is co-discoverer of ultraconserved elements—stretches of non-coding DNA that are better conserved and under more human purifying selection than coding DNA is—and his laboratory strives to understand the many genomic regions that are conserved between human and other vertebrates, whose functions remain unknown in whole, or in part. Particular interest is paid to the many thousands of regions involved in gene transcription regulation during vertebrate development. The major interests are to (1) study the origins and evolution of these regions, (2) how they encode their individual as well as combined roles, (3) how they contribute to human disease, and (4) how they contribute to speciation. Combined, these goals provide insight into the evolutionary history of our genome, including the emergence of novel beneficial traits as well as deleterious phenotypes. Dr. Bejerano is a two time recipient of the best paper by a young scientist award (RECOMB 1999, 2003), and his lab is supported by the Edward Mallinckrodt Jr. Foundation. Please see http://bejerano.stanford.edu/ Personal Gill Bejerano holds a BSc, summa cum laude, in Mathematics, Physics, and Computer Science, and a PhD in Computer Science from the Hebrew University of Jerusalem, Israel. Twice recipient of the RECOMB best paper by a young scientist award, and a former Eshkol pre-doctoral Scholar and HHMI postdoc with David Haussler at UC Santa Cruz. Gill is currently an Assistant Professor in the Department of Developmental Biology and the Department of Computer Science at Stanford university. As co-discoverer of ultraconserved elements, his research focuses on deciphering the function and evolution of the non-coding regions of the Human Genome. See http://bejerano.stanford.edu/ Lab 80 words: Gill Bejerano. Understand the Human Genome through vertebrate comparative, functional and paleo-genomics. The functional landscape of the Human Genome and its evolution, with particular focus on vertebrate gene regulation and its contributions to morphological diversity, development and human disease. Encoding, functions, origins and evolution of proximal and distal cis-acting regulatory elements. The paradoxical existence of ultraconserved elements. Co-option of mobile DNA elements (repeats) as a driving force in vertebrate evolution. Interpreting ancestral genomes. See http://bejerano.stanford.edu 105 words: Gill Bejerano's lab focuses on the study of the human genome. As co-discoverer of ultraconserved elements, Gill's lab strives to understand the many genomic regions that are conserved between human and other vertebrates, whose functions remain unknown in whole, or in part. Particular interest is paid to the thousands of regions involved in gene transcription regulation during vertebrate development. The major interests are to (1) study the origins and evolution of these regions, (2) how they encode their individual as well as combined roles, and (3) how they contribute to human disease. Combined, these goals provide insight into the evolutionary history of our genome, including the emergence of novel beneficial traits as well as deleterious phenotypes. See http://bejerano.stanford.edu