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The MSigDB Cancer Modules
1 ontology contains gene sets from mining large collections of cancer-oriented microarray data2 and combining it with "modules" obtained from sources such as KEGG and GO. The ontology consists of the 456 modules whose expression is significantly altered in a variety of cancer conditions.


The human ontology contains 456 gene sets, 7,918 genes, and 47,511 associations.

The ontology is not available for mouse.


All data for this ontology was downloaded on March 11, 2009 (MSigDB version 2.5).


Ref Notes
1 Subramanian, A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50.
2 Segal, E., Friedman, N., Koller, D., Regev, A. A module map showing conditional activity of expression modules in cancer, Nat Genet. 2004 Oct; 36(10):1090-8.
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