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Description

The MSigDB Cancer Neighborhood1 ontology contains gene sets from mining large collections of cancer-oriented microarray data. Each gene set is defined by correlated expression with one of 380 cancer-associated genes2 .

Statistics

The human ontology contains 427 gene sets, 4,717 genes, and 41,713 associations.

The ontology is not available for mouse.

Download

All data for this ontology was downloaded on March 11, 2009 (MSigDB version 2.5).

References

Footnotes
Ref Notes
1 Subramanian, A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50.
2 Brentani, H., et al. The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags, Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13418-23.
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