The MSigDB Predicted Promoter Motifs1 ontology contains sets of genes that share a transcription factor binding site in their promoters. The binding sites are as predicted based on definitions from the TransFac database (version 7.4)2 .
The human ontology contains 615 gene sets, 11,777 genes, and 154,911 associations.
The mouse ontology contains 615 gene sets, 9,117 genes, and 127,459 associations.
All data for this ontology was downloaded on March 11, 2009 (MSigDB version 2.5).
|1||Subramanian, A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50.|
|2||Wingender, E., et al. TRANSFAC: an integrated system for gene expression regulation, Nucleic Acids Res. 2000 Jan 1; 28(1):316-9.|