The MSigDB Predicted Promoter Motifs1 ontology contains sets of genes that share a transcription factor binding site in their promoters. The binding sites are as predicted based on definitions from the TransFac database (version 7.4)2 .
The human hg19 ontology contains 615 gene sets, 8,932 genes, and 123,255 associations.
The human hg18 ontology contains 615 gene sets, 8,940 genes, and 123,318 associations.
The mouse mm9 ontology contains 615 gene sets, 8,233 genes, and 116,715 associations.
All data for this ontology was downloaded on September 30, 2010 (MSigDB version 3.0).
GREAT v1.2 MSigDB Predicted Promoter Motifs statistics are available here.
|1||Subramanian, A., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50.|
|2||Wingender, E., et al. TRANSFAC: an integrated system for gene expression regulation, Nucleic Acids Res. 2000 Jan 1; 28(1):316-9.|