GREAT Source Code
We soon will offer for download our implementation of the core calculation engine logic used by GREAT to calculate enrichments is available for download here. To uncompress the file into your directory, execute the command
tar xzvf great.tar.gz
Instructions to complete the build are available within the README.txt file included in the tarball.. The logic for associating regions with genes and calculating enrichments is also fully described in our Nature Biotechnology paper.
Our full GREAT application is very specific to our systems, which many hardcoded values and other dependencies on our setup. So, instead of providing a setup-specific application, we provide an implementation of the generally usable core calculation logic which can be used readily to build a version of GREAT that works with your system.
All of the data included in the GREAT ontologies is publicly available, and we provide links or references for every ontology. We do not currently offer our processed ontology data for download, but all data is available from the original sources.