- A decent genome assembly.
- A decent gene set.
- Gene annotations. Typically in the form of an ontology, and gene to ontology term mappings.
- A community of researchers actually taking measurements in said species.
For species near enough to human for our own cis-regulation interests - practically all vertebrates - vertebrate species, you can help us consider additional species by sending us specific links to rich gene annotation resources unique to your species of interest.
For species more distantly related to human (say e.g. fly or arabidopsis) we will likely not do the curation ourselves. However, if you are seriously interested and capable we can consider sharing our file format requirements with you and have you contribute this species into GREAT.