Cory Y McLean, Dave Bristor, Michael Hiller, Shoa L Clarke, Bruce T Schaar, Craig B Lowe, Aaron M Wenger, and Gill Bejerano. "GREAT improves functional interpretation of cis-regulatory regions". Nat. Biotechnol.28(5):495-501, 2010.
Over the long run, the best way to assure the continued availability and development of GREAT is for us to be able to show its relevance and contribution to biomedical research. We thank you for your support!
We really appreciate people's supportive e-mails and re-cap a handful of them here to encourage folks to take the plunge.
Subject: your tool is cool
Date: May 4, 2010
This is not a ... ad. GREAT is awesome, we have been playing
around with it quite a bit.
you certainly will be referenced in a paper that we want to submit by
the end of this month. And I suspect many more after that.
Subject: Re: great
Date: May 5, 2010
Hey guys, I had a chance to try out GREAT for a bit with our ...
chip-seq data. It looks like an amazing tool and it's way ahead
of anything else out there for chipseq-related functional analysis. My
favorite part is being able to click through each annotation and
seeing the actual genes that were assigned.. very fancy and cool. That
and the integration with the mouse phenotype ontologies--a big thing
that other tools dont' have. Anyway we'll definitely be using it and
I'll be sure to spread the word!
Date: October 19, 2010
Dear GREAT developers
I find this tool very useful in analyzing my ChIP-seq peaks, especially
after being quite frustrated using other tools to get insight into the
functions/pathways associated with my TF. ...