Skip to end of metadata
Go to start of metadata

You are viewing an old version of this page. View the current version.

Compare with Current View Page History

« Previous Version 12 Next »

GREAT Source Code

Our implementation of the core calculation logic used by GREAT is now available for download. This package is written in C and includes two tools:

  1. A tool to calculate computationally-defined gene regulatory domains.
  2. A tool to calculate the genomic region-based binomial enrichment p-value for ontology terms given the regulatory domains of genes annotated with the term and the input regions associated with the term.

To download and install the tools, perform the following steps:

  1. Download the source code tarball
  2. Unpack the tarball using the command 'tar xzvf greatTools.tar.gz'
  3. Follow installation instructions given in the README.txt file

The logic for associating regions with genes and calculating enrichments is also completely described in our Nature Biotechnology paper.

Ontology Data

All of the data included in the GREAT ontologies is publicly available, and we provide links or references for every ontology. We do not currently offer our processed ontology data for download, but all data is available from the original sources. Additionally, the GREAT web tool offers numerous "Export" functions to save all ontology data as it pertains to your sets.

  • No labels