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ACTIN-RELATED PROTEIN T1; ACTRT1

Alternative titles; symbols

ARPT1

Gene map locus Xq25

TEXT

CLONING

Heid et al. (2002) purified bovine Arpt1 from the calyx fraction of epididymal sperm heads. Using peptide sequences to search genomic and EST databases, they identified human ARPT1. The deduced 376-amino acid protein shares 49.3% amino acid identity with beta-actin (ACTB; 102630) and 75.5% identity with ARPT2 (608535). Both ARPT1 and ARPT2 contain several cysteine residues not found in beta-actin or other ARPs. Bovine Arpt1 showed an apparent molecular mass of about 40 kD.

MAPPING

Heid et al. (2002) stated that the ACTRT1 gene maps to chromosome Xq25.

REFERENCES

1. Heid, H. W.; Figge, U.; Winter, S.; Kuhn, C.; Zimbelmann, R.; Franke, W. W. :

Novel actin-related proteins Arp-T1 and Arp-T2 as components of the cytoskeletal calyx of the mammalian sperm head. Exp. Cell Res. 279: 177-187, 2002.
PubMed ID : 12243744

CREATION DATE

Patricia A. Hartz : 3/16/2004

EDIT HISTORY

alopez : 6/21/2006
mgross : 3/16/2004

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